Chiefs vs 49ers Prediction, Bet Builder Tips & Odds

By Scott Miller, Senior NFL Analyst | Published: 6 months ago | 4 min read

Kansas City Chiefs

American Football NFL Levi's Stadium Mon 21 Oct 04:25

San Francisco 49ers

  1. Prediction
  2. Bet Builder
  3. Odds
  4. Player Props
  5. Stats
  6. Team News
  7. Lineups
  8. Injuries
  9. Standings

Niners Should Have the Edge Against Chiefs

We’re heading to the Moneyline and our betting prediction is for the Niners to win. They have a strong chance of beating the Chiefs and the 1.91 makes plenty of appeal.

Previous H2H Saw Chiefs Win in Overtime

Kansas City Chiefs have won their previous five games. The latest was a 26-13 home triumph at GEHA Field at Arrowhead Stadium against New Orleans Saints. The Chiefs gained 321 passing and 139 rushing yards, making 460 yards in total. They scored 2 touchdowns. Both TD’s were rushing touchdowns.

San Francisco 49ers won their last game 36-24. This was a road victory at Lumen Field against Seattle Seahawks. The 49ers managed a 483 yard gain, composed of 228 rushing and 255 passing yards. They scored 4 touchdowns and picked up 21 first downs.

The last head-to-head saw the Chiefs claim a 25-22 (OT) win over the Niners at Allegiant Stadium. It’s been a succession of Chiefs wins in the past 3 H2H meetings.

Quarterbacks

Patrick Mahomes
Brock Purdy

Expert NFL Analysis

Our expert NFL handicappers study the latest form, while injuries and suspensions can also affect the potential outcome. Before coming up with a verdict, we combine this data with the latest stats.

Key Chiefs vs 49ers stats:

  • 49ers have won 16 of their last 20 games at home.
  • 49ers have won 4 of their last 5 games at home.

Chiefs vs 49ers Prediction

There’s an attractive 1.91 that the Niners are able to get the better of their opponents. This pick can be wagered on the Moneyline for this NFL showdown.

If you’re looking for more attractive odds, then the Niners on the Double Result lines could be a way forward. You need them to lead at the halfway stage and then claim a win.

Niners Moneyline Probability

When you look at the latest odds, our pick has a 52.4% chance of landing a return. After careful examination, our analysts have this probability somewhere between 55-60%. This is why we regard this as a value bet.

Our Pick

49ers Moneyline @ 1.91 Bet Now bet365 logo
Gamble responsibly 18+. All odds are correct at time of publishing and are subject to change. To use the Bookmaker Live Streaming services you will need to be logged in and have a funded account or to have placed a bet in the last 24 hours. Geo-restrictions apply.
Published 08:26, 19 October 2024

Chiefs vs 49ers Bet Builder Tips

Moneyline 49ers
Anytime Touchdown Deebo Samuel
Receiving Yards George Kittle Over 53.5

Our same game parlay pick includes 49ers on the moneyline, Deebo Samuel (49ers) anytime TD scorer and George Kittle (49ers) having Over 53.5 receiving yards.

Should you want to back different outcomes for the same football game, then a bet builder will suit your needs. The betting sites create this personalised wagering tool where you can hand-pick different outcomes and combine the odds together.

T&C apply. Gamble responsibly 18+

Correct Score Prediction

Chiefs Chiefs logo 21 - 23 49ers logo 49ers

There might not be too much between these teams, with our correct score prediction being a 23-21 win for the 49ers. There are enormous odds available when it comes to this pick.

Chiefs vs 49ers Odds

The odds and lines are updated on a frequent basis. You might therefore find that they are different to the ones listed for the betting predictions and bet builder tips.

Books Think the Game Could Go Either Way

San Francisco 49ers have been given Moneyline odds of 1.76 against Kansas City Chiefs who are 2.08. The leading sportsbooks give the hosts a 57% chance of success.

The current spread is 2.5 and total points is 47. There is no denying the popularity of betting on the Totals. If you fancy Under 47, then the odds are 1.89.

National Football League fans are spoilt for choice thanks to the wide range of team props and game lines which are available for every clash on the coupon. Head to the betting sites and find the best value wagers.

Player Props

We’re fond of the player and quarterback props as an alternative to betting on the game lines. The gambling sites will have Player Kicking Points, Rushing Yards and Longest Rushing Attempt among the choices and you can take a view.

Jordan Mason Favorite to Score First TD

Jordan Mason is available at 1.83 when it comes to Anytime Touchdown Scorer. The favorite is now priced at odds of 6.40 to score the first TD.

Touchdown

Receiving Yards

Rushing Yards

Passing Yards

Best Betting Offers

Last 5 & H2H

Team Stats

Latest regular season and playoff games stats.

Kansas City Chiefs logo Kansas City Chiefs Stats

San Francisco 49ers logo San Francisco 49ers Stats

Moneyline

  • 10 wins and 0 defeats in the last 10 games
  • 8 wins and 2 defeats in the last 10 games on the road

Moneyline

  • 5 wins and 5 defeats in the last 10 games
  • 6 wins and 4 defeats in the last 10 home games

Point Spread

Point Spread

Total Points

Total Points

Game Stats

Last 10 Games

Game Stats

Last 10 Games
Last 10 Games on the Road
Last 10 Home Games

Team News

Kansas City Chiefs @ San Francisco 49ers Lineups

San Francisco 49ers

Manager:
Kyle Shanahan
0
Renardo Green
3
Mitch Wishnowsky
10
Ronnie Bell
14
Ricky Pearsall
17
Brandon Allen
18
Chris Conley
19
Jacob Cowing
22
Isaac Yiadom
30
George Odum
31
Isaac Guerendo
32
Patrick Taylor Jr.
33
Rock Ya-Sin
38
Jaylen Mahoney
41
Anders Carlson
45
Demetrius Flannigan-Fowles
46
Taybor Pepper
48
Tatum Bethune
51
Robert Beal Jr.
63
Nick Zakelj
74
Spencer Burford
76
Jaylon Moore
82
Eric Saubert
88
Jake Tonges
90
Kevin Givens
91
Sam Okuayinonu
93
Kalia Davis

Kansas City Chiefs

Manager:
Andy Reid
2
Joshua Williams
7
Harrison Butker
11
Carson Wentz
12
Jared Wiley
13
Nazeeh Johnson
14
Matt Araiza
17
Mecole Hardman
21
Jaden Hicks
24
Skyy Moore
27
Chamarri Conner
30
Christian Roland-Wallace
34
Samaje Perine
41
James Winchester
42
Carson Steele
43
Jack Cochrane
44
Cam Jones
48
Cole Christiansen
60
Hunter Nourzad
66
Mike Caliendo
76
Kingsley Suamataia
84
Justin Watson
89
Jody Fortson
91
Derrick Nnadi
94
Malik Herring
98
Tershawn Wharton
99
Cameron Thomas

San Francisco 49ers Substitutes

  • 1 Deebo Samuel
  • 2 Deommodore Lenoir
  • 6 Malik Mustapha
  • 7 Charvarius Ward
  • 11 Brandon Aiyuk
  • 13 Brock Purdy
  • 24 Jordan Ponchez-Mason
  • 27 Ji'Ayir Brown
  • 44 Kyle Juszczyk
  • 53 Dee Winters
  • 54 Fred Warner
  • 56 Leonard Floyd
  • 59 De'Vondre Campbell
  • 64 Jake Brendel
  • 65 Aaron Banks
  • 68 Colton McKivitz
  • 71 Trent Williams
  • 77 Dominick Puni
  • 85 George Kittle
  • 92 Jordan Elliott
  • 97 Nick Bosa
  • 99 Maliek Collins

Kansas City Chiefs Substitutes

  • 1 Xavier Worthy
  • 6 Bryan Cook
  • 9 JuJu Smith-Schuster
  • 15 Patrick Mahomes
  • 20 Justin Reid
  • 22 Trent McDuffie
  • 23 Drue Tranquill
  • 29 Kareem Hunt
  • 32 Nick Bolton
  • 35 Jaylen Watson
  • 52 Creed Humphrey
  • 54 Leo Chenal
  • 56 George Karlaftis
  • 62 Joe Thuney
  • 64 Wanya Morris
  • 65 Trey Smith
  • 69 Mike Pennel
  • 74 Jawaan Taylor
  • 83 Noah Gray
  • 87 Travis Kelce
  • 95 Chris Jones
  • 97 Felix Anudike-Uzomah

Kansas City Chiefs Injuries

Type
Name
Info
Hollywood Brown
Shoulder
Mike Danna
Pectoral
Jaaron Hayek
Shoulder
McKade Mettauer
Knee - MCL
Charles Omenihu
Knee - ACL
Isiah Pacheco
Lower Leg
Rashee Rice
Knee
JuJu Smith-Schuster
Hamstring
BJ Thompson
Chest

San Francisco 49ers Injuries

Type
Name
Info
Jon Feliciano
Knee
Kevin Givens
Groin
Dre Greenlaw
Achilles
Yetur Gross-Matos
Knee
Javon Hargrave
Triceps
Talanoa Hufanga
Wrist
Drake Jackson
Knee
Jauan Jennings
Hip
Darrell Luter
Pelvis
Christian McCaffrey
Achilles
Elijah Mitchell
Hamstring
Jake Moody
Ankle
Ricky Pearsall
Chest
Curtis Robinson
Knee - ACL
Ambry Thomas
Forearm
Matthew Wright
Shoulder

Previous Kansas City Chiefs Lineups

08 Oct NFL
Saints 13-26 Chiefs
30 Sep NFL
Chiefs 17-10 Chargers
23 Sep NFL
Chiefs 22-17 Falcons
16 Sep NFL
Bengals 25-26 Chiefs
06 Sep NFL
Ravens 20-27 Chiefs
12 Feb NFL Playoffs
49ers 22-25 Chiefs
29 Jan NFL Playoffs
Chiefs 17-10 Ravens
22 Jan NFL Playoffs
Chiefs 27-24 Bills
14 Jan NFL Playoffs
Dolphins 7-26 Chiefs
08 Jan NFL
Chiefs 13-12 Chargers

Previous San Francisco 49ers Lineups

11 Oct NFL
49ers 36-24 Seahawks
07 Oct NFL
Cardinals 24-23 49ers
30 Sep NFL
Patriots 13-30 49ers
23 Sep NFL
49ers 24-27 Rams
16 Sep NFL
49ers 17-23 Vikings
10 Sep NFL
Jets 19-32 49ers
12 Feb NFL Playoffs
49ers 22-25 Chiefs
29 Jan NFL Playoffs
Lions 31-34 49ers
21 Jan NFL Playoffs
Packers 21-24 49ers
08 Jan NFL
Rams 21-20 49ers

NFL Standings Select Season

AFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Bills 13 4 0 0.765 525 368 157 8-0-0 5-4-0 5-1-0 9-3-0 3-2-0 1L
Dolphins 8 9 0 0.471 345 364 -19 5-3-0 3-6-0 3-3-0 6-6-0 3-2-0 1L
Jets 5 12 0 0.294 338 404 -66 3-5-0 2-7-0 2-4-0 5-7-0 2-3-0 1W
Patriots 4 13 0 0.235 289 417 -128 2-6-0 2-7-0 2-4-0 3-9-0 1-4-0 1W
AFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Ravens 12 5 0 0.706 518 361 157 6-2-0 6-3-0 4-2-0 8-4-0 4-1-0 4W
Steelers 10 7 0 0.588 380 347 33 5-3-0 5-4-0 3-3-0 7-5-0 1-4-0 4L
Bengals 9 8 0 0.529 472 434 38 3-5-0 6-3-0 3-3-0 6-6-0 5-0-0 5W
Browns 3 14 0 0.176 258 435 -177 2-6-0 1-8-0 2-4-0 3-9-0 0-5-0 6L
AFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Texans 10 7 0 0.588 372 372 0 5-3-0 5-4-0 5-1-0 8-4-0 3-2-0 1W
Colts 8 9 0 0.471 377 427 -50 5-3-0 3-6-0 3-3-0 7-5-0 3-2-0 1W
Jaguars 4 13 0 0.235 320 435 -115 3-5-0 1-8-0 3-3-0 4-8-0 2-3-0 1L
Titans 3 14 0 0.176 311 460 -149 1-7-0 2-7-0 1-5-0 3-9-0 0-5-0 6L
AFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Chiefs 15 2 0 0.882 385 326 59 8-0-0 7-2-0 5-1-0 10-2-0 4-1-0 1L
Chargers 11 6 0 0.647 402 301 101 5-3-0 6-3-0 4-2-0 8-4-0 3-2-0 3W
Broncos 10 7 0 0.588 425 311 114 6-2-0 4-5-0 3-3-0 6-6-0 3-2-0 1W
Raiders 4 13 0 0.235 309 434 -125 2-6-0 2-7-0 0-6-0 3-9-0 2-3-0 1L
NFC East W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Eagles 14 3 0 0.824 463 303 160 8-1-0 6-2-0 5-1-0 9-3-0 4-1-0 2W
Commanders 12 5 0 0.706 485 391 94 7-2-0 5-3-0 4-2-0 9-3-0 5-0-0 5W
Cowboys 7 10 0 0.412 350 468 -118 2-7-0 5-3-0 3-3-0 5-7-0 2-3-0 2L
Giants 3 14 0 0.176 273 415 -142 1-8-0 2-6-0 0-6-0 1-11-0 1-4-0 1L
NFC North W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Lions 15 2 0 0.882 564 342 222 7-2-0 8-0-0 6-0-0 11-1-0 4-1-0 3W
Vikings 14 3 0 0.824 432 332 100 8-1-0 6-2-0 4-2-0 9-3-0 4-1-0 1L
Packers 11 6 0 0.647 460 338 122 6-3-0 5-3-0 1-5-0 6-6-0 2-3-0 2L
Bears 5 12 0 0.294 310 370 -60 4-5-0 1-7-0 1-5-0 3-9-0 1-4-0 1W
NFC South W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Buccaneers 10 7 0 0.588 502 385 117 5-4-0 5-3-0 4-2-0 8-4-0 4-1-0 2W
Falcons 8 9 0 0.471 389 423 -34 4-5-0 4-4-0 4-2-0 7-5-0 2-3-0 2L
Saints 5 12 0 0.294 338 398 -60 3-6-0 2-6-0 2-4-0 4-8-0 1-4-0 4L
Panthers 5 12 0 0.294 341 534 -193 3-6-0 2-6-0 2-4-0 4-8-0 2-3-0 1W
NFC West W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Rams 10 7 0 0.588 367 386 -19 5-4-0 5-3-0 4-2-0 6-6-0 4-1-0 1L
Seahawks 10 7 0 0.588 375 368 7 3-6-0 7-1-0 4-2-0 6-6-0 3-2-0 2W
Cardinals 8 9 0 0.471 400 379 21 6-3-0 2-6-0 3-3-0 4-8-0 2-3-0 1W
49ers 6 11 0 0.353 389 436 -47 4-5-0 2-6-0 1-5-0 4-8-0 1-4-0 4L
AFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Chiefs 15 2 0 0.882 385 326 59 8-0-0 7-2-0 5-1-0 10-2-0 4-1-0 1L
Bills 13 4 0 0.765 525 368 157 8-0-0 5-4-0 5-1-0 9-3-0 3-2-0 1L
Ravens 12 5 0 0.706 518 361 157 6-2-0 6-3-0 4-2-0 8-4-0 4-1-0 4W
Texans 10 7 0 0.588 372 372 0 5-3-0 5-4-0 5-1-0 8-4-0 3-2-0 1W
Chargers 11 6 0 0.647 402 301 101 5-3-0 6-3-0 4-2-0 8-4-0 3-2-0 3W
Steelers 10 7 0 0.588 380 347 33 5-3-0 5-4-0 3-3-0 7-5-0 1-4-0 4L
Broncos 10 7 0 0.588 425 311 114 6-2-0 4-5-0 3-3-0 6-6-0 3-2-0 1W
Bengals 9 8 0 0.529 472 434 38 3-5-0 6-3-0 3-3-0 6-6-0 5-0-0 5W
Colts 8 9 0 0.471 377 427 -50 5-3-0 3-6-0 3-3-0 7-5-0 3-2-0 1W
Dolphins 8 9 0 0.471 345 364 -19 5-3-0 3-6-0 3-3-0 6-6-0 3-2-0 1L
Jets 5 12 0 0.294 338 404 -66 3-5-0 2-7-0 2-4-0 5-7-0 2-3-0 1W
Raiders 4 13 0 0.235 309 434 -125 2-6-0 2-7-0 0-6-0 3-9-0 2-3-0 1L
Jaguars 4 13 0 0.235 320 435 -115 3-5-0 1-8-0 3-3-0 4-8-0 2-3-0 1L
Titans 3 14 0 0.176 311 460 -149 1-7-0 2-7-0 1-5-0 3-9-0 0-5-0 6L
Patriots 4 13 0 0.235 289 417 -128 2-6-0 2-7-0 2-4-0 3-9-0 1-4-0 1W
Browns 3 14 0 0.176 258 435 -177 2-6-0 1-8-0 2-4-0 3-9-0 0-5-0 6L
NFC Conference W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Lions 15 2 0 0.882 564 342 222 7-2-0 8-0-0 6-0-0 11-1-0 4-1-0 3W
Eagles 14 3 0 0.824 463 303 160 8-1-0 6-2-0 5-1-0 9-3-0 4-1-0 2W
Rams 10 7 0 0.588 367 386 -19 5-4-0 5-3-0 4-2-0 6-6-0 4-1-0 1L
Buccaneers 10 7 0 0.588 502 385 117 5-4-0 5-3-0 4-2-0 8-4-0 4-1-0 2W
Vikings 14 3 0 0.824 432 332 100 8-1-0 6-2-0 4-2-0 9-3-0 4-1-0 1L
Commanders 12 5 0 0.706 485 391 94 7-2-0 5-3-0 4-2-0 9-3-0 5-0-0 5W
Packers 11 6 0 0.647 460 338 122 6-3-0 5-3-0 1-5-0 6-6-0 2-3-0 2L
Seahawks 10 7 0 0.588 375 368 7 3-6-0 7-1-0 4-2-0 6-6-0 3-2-0 2W
Falcons 8 9 0 0.471 389 423 -34 4-5-0 4-4-0 4-2-0 7-5-0 2-3-0 2L
Cowboys 7 10 0 0.412 350 468 -118 2-7-0 5-3-0 3-3-0 5-7-0 2-3-0 2L
Cardinals 8 9 0 0.471 400 379 21 6-3-0 2-6-0 3-3-0 4-8-0 2-3-0 1W
49ers 6 11 0 0.353 389 436 -47 4-5-0 2-6-0 1-5-0 4-8-0 1-4-0 4L
Saints 5 12 0 0.294 338 398 -60 3-6-0 2-6-0 2-4-0 4-8-0 1-4-0 4L
Bears 5 12 0 0.294 310 370 -60 4-5-0 1-7-0 1-5-0 3-9-0 1-4-0 1W
Panthers 5 12 0 0.294 341 534 -193 3-6-0 2-6-0 2-4-0 4-8-0 2-3-0 1W
Giants 3 14 0 0.176 273 415 -142 1-8-0 2-6-0 0-6-0 1-11-0 1-4-0 1L
NFL Team W L T PCT PF PA N. Pts Home Road Div Conf Last 5 Strk
Lions 15 2 0 0.882 564 342 222 7-2-0 8-0-0 6-0-0 11-1-0 4-1-0 3W
Chiefs 15 2 0 0.882 385 326 59 8-0-0 7-2-0 5-1-0 10-2-0 4-1-0 1L
Vikings 14 3 0 0.824 432 332 100 8-1-0 6-2-0 4-2-0 9-3-0 4-1-0 1L
Eagles 14 3 0 0.824 463 303 160 8-1-0 6-2-0 5-1-0 9-3-0 4-1-0 2W
Bills 13 4 0 0.765 525 368 157 8-0-0 5-4-0 5-1-0 9-3-0 3-2-0 1L
Ravens 12 5 0 0.706 518 361 157 6-2-0 6-3-0 4-2-0 8-4-0 4-1-0 4W
Commanders 12 5 0 0.706 485 391 94 7-2-0 5-3-0 4-2-0 9-3-0 5-0-0 5W
Packers 11 6 0 0.647 460 338 122 6-3-0 5-3-0 1-5-0 6-6-0 2-3-0 2L
Chargers 11 6 0 0.647 402 301 101 5-3-0 6-3-0 4-2-0 8-4-0 3-2-0 3W
Broncos 10 7 0 0.588 425 311 114 6-2-0 4-5-0 3-3-0 6-6-0 3-2-0 1W
Texans 10 7 0 0.588 372 372 0 5-3-0 5-4-0 5-1-0 8-4-0 3-2-0 1W
Rams 10 7 0 0.588 367 386 -19 5-4-0 5-3-0 4-2-0 6-6-0 4-1-0 1L
Steelers 10 7 0 0.588 380 347 33 5-3-0 5-4-0 3-3-0 7-5-0 1-4-0 4L
Seahawks 10 7 0 0.588 375 368 7 3-6-0 7-1-0 4-2-0 6-6-0 3-2-0 2W
Buccaneers 10 7 0 0.588 502 385 117 5-4-0 5-3-0 4-2-0 8-4-0 4-1-0 2W
Bengals 9 8 0 0.529 472 434 38 3-5-0 6-3-0 3-3-0 6-6-0 5-0-0 5W
Cardinals 8 9 0 0.471 400 379 21 6-3-0 2-6-0 3-3-0 4-8-0 2-3-0 1W
Falcons 8 9 0 0.471 389 423 -34 4-5-0 4-4-0 4-2-0 7-5-0 2-3-0 2L
Colts 8 9 0 0.471 377 427 -50 5-3-0 3-6-0 3-3-0 7-5-0 3-2-0 1W
Dolphins 8 9 0 0.471 345 364 -19 5-3-0 3-6-0 3-3-0 6-6-0 3-2-0 1L
Cowboys 7 10 0 0.412 350 468 -118 2-7-0 5-3-0 3-3-0 5-7-0 2-3-0 2L
49ers 6 11 0 0.353 389 436 -47 4-5-0 2-6-0 1-5-0 4-8-0 1-4-0 4L
Panthers 5 12 0 0.294 341 534 -193 3-6-0 2-6-0 2-4-0 4-8-0 2-3-0 1W
Bears 5 12 0 0.294 310 370 -60 4-5-0 1-7-0 1-5-0 3-9-0 1-4-0 1W
Saints 5 12 0 0.294 338 398 -60 3-6-0 2-6-0 2-4-0 4-8-0 1-4-0 4L
Jets 5 12 0 0.294 338 404 -66 3-5-0 2-7-0 2-4-0 5-7-0 2-3-0 1W
Jaguars 4 13 0 0.235 320 435 -115 3-5-0 1-8-0 3-3-0 4-8-0 2-3-0 1L
Raiders 4 13 0 0.235 309 434 -125 2-6-0 2-7-0 0-6-0 3-9-0 2-3-0 1L
Patriots 4 13 0 0.235 289 417 -128 2-6-0 2-7-0 2-4-0 3-9-0 1-4-0 1W
Browns 3 14 0 0.176 258 435 -177 2-6-0 1-8-0 2-4-0 3-9-0 0-5-0 6L
Giants 3 14 0 0.176 273 415 -142 1-8-0 2-6-0 0-6-0 1-11-0 1-4-0 1L
Titans 3 14 0 0.176 311 460 -149 1-7-0 2-7-0 1-5-0 3-9-0 0-5-0 6L

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